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DOI: 10.48087/BJMS.2026.130320
Authors: Asma MOUS¹,Lotfi TALEB¹, Abdelbaki BOUKERCHE²
Affiliations: 1- Faculté de Médecine Dr Benaouda Benzerdjeb, Université Abou Bekr Belkaid de Tlemcen ; Service de Radiothérapie, EHS.CAC Ahmed Ben Bella, Tlemcen – Algérie. 2- Faculté de Médecine, Université d’Oran 1 ; Service de Radiothérapie, EHS en oncologie Emir Abdelkader d’Oran – Algérie.
Abstract
The association of glioblastoma and cerebral sarcoma constitutes an exceptionally rare and complex clinicopathological entity, first described by Stroebe in 1895. We present the case of a 30-year-old woman with a personal history of neurofibromatosis type 1 who was diagnosed with a mixed brain tumor. The diagnosis of glioblastoma associated with sarcoma was confirmed by histopathological and immunohistochemical examination. Therapeutic management consisted of two neurosurgical resections one month apart, followed by concomitant chemoradiotherapy and subsequently adjuvant chemotherapy.
Keywords: glioblastoma, sarcoma, central nervous system, radiotherapy, chemotherapy.