{"id":803,"date":"2026-03-30T06:03:19","date_gmt":"2026-03-30T06:03:19","guid":{"rendered":"https:\/\/batnajms.net\/?p=803"},"modified":"2026-03-30T06:03:41","modified_gmt":"2026-03-30T06:03:41","slug":"bennaoum","status":"publish","type":"post","link":"https:\/\/batnajms.net\/index.php\/2026\/03\/30\/bennaoum\/","title":{"rendered":"Hemostasis disorders predisposing to portal vein thrombosis"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\" id=\"block-c2f138d4-0208-4b99-af09-93c83eb26d35\"><strong><a href=\"https:\/\/batnajms.net\/wp-content\/uploads\/Archives\/2026\/04\/BJMS_Bennaoum.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Fulltext\u00a0<\/strong><\/a>(PDF)<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>DOI<\/strong>: 10.48087\/BJMS.2026.130402<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Authors:<\/strong>\u00a0Mohammed Nazim BENNAOUM<sup>1,2<\/sup>, Abdelmadjid MEGUEDAD<sup> 1,3<\/sup>, Affaf ADDA<sup>1,2<\/sup>, Chafika MANOUNI<sup>1,3<\/sup>, Mohamed CHEKKAL<sup>1,2<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Affiliations:<\/strong>\u00a01- Facult\u00e9 de m\u00e9decine, Universit\u00e9 Oran 1 Ahmed Ben Bella<em>. 2- S<\/em>ervice d\u2019h\u00e9mobiologie et banque de sang, EHU Oran. 3- Service d\u2019h\u00e9pato-gastro-enterologie, EHU Oran \u2013 Alg\u00e9rie.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Abstract<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Introduction: <\/strong>Portal vein thrombosis is characterized by the formation of a thrombus within the portal vein. Development of portal vein thrombosis can be secondary to genetic abnormalities, circumstantial factors, iatrogenic or related to other pathologies. <strong>Material and methods:<\/strong> In this case study, 67 patients with portal vein thrombosis and 105 healthy individuals as controls were enrolled. We studied the relationship between hemostasis disorders and development of portal vein thrombosis. <strong>Results:<\/strong> The mean age of the patients was 44 years with a sex ratio of 0.59. Antithrombin deficiency was found in 37% of patients and 8% of controls. Protein C deficiency was observed in 40% of patients and was absent in controls. Protein S deficiency was present in 27% of patients and 3% of controls. Consequently, a significant statistical relation was found between development of portal vein thrombosis and deficit of physiological coagulation inhibitors. Factor V Leiden and antiphospholipid antibodies were found in 2% and 3% of patients respectively, however, the relation with portal vein thrombosis was not statistically established. Combined deficit of more than one physiological coagulation inhibitor was found in 48% of patients. <strong>Conclusion:<\/strong> Deficiency of physiological coagulation inhibitors was a major cause of portal vein thrombosis. However, the constitutional or acquired origin of these defects has not been determined.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Keywords<\/strong><strong>: <\/strong>Portal vein thrombosis, Physiological coagulation inhibitors, Hemostasis.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fulltext\u00a0(PDF) DOI: 10.48087\/BJMS.2026.130402 Authors:\u00a0Mohammed Nazim BENNAOUM1,2, Abdelmadjid MEGUEDAD 1,3, Affaf ADDA1,2, Chafika MANOUNI1,3, Mohamed CHEKKAL1,2 Affiliations:\u00a01- Facult\u00e9 de m\u00e9decine, Universit\u00e9 Oran 1 Ahmed Ben Bella. 2- Service d\u2019h\u00e9mobiologie et banque de sang, EHU Oran. 3- Service d\u2019h\u00e9pato-gastro-enterologie, EHU Oran \u2013 Alg\u00e9rie. Abstract Introduction: Portal vein thrombosis is characterized by the formation of a thrombus within &hellip; <a href=\"https:\/\/batnajms.net\/index.php\/2026\/03\/30\/bennaoum\/\" class=\"more-link\">Continuer la lecture de <span class=\"screen-reader-text\">Hemostasis disorders predisposing to portal vein thrombosis<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-803","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/803","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/comments?post=803"}],"version-history":[{"count":1,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/803\/revisions"}],"predecessor-version":[{"id":804,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/803\/revisions\/804"}],"wp:attachment":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/media?parent=803"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/categories?post=803"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/tags?post=803"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}