{"id":702,"date":"2026-03-01T16:37:50","date_gmt":"2026-03-01T16:37:50","guid":{"rendered":"https:\/\/batnajms.net\/?p=702"},"modified":"2026-03-02T14:47:50","modified_gmt":"2026-03-02T14:47:50","slug":"ghemri","status":"publish","type":"post","link":"https:\/\/batnajms.net\/index.php\/2026\/03\/01\/ghemri\/","title":{"rendered":"Is severe sleep apnea syndrome associated with more extensive coronary involvement? Angiographic and clinical analysis in 241 patients admitted for a first NSTE-ACS: an Algerian prospective study"},"content":{"rendered":"\n

Fulltext <\/strong><\/a>(PDF)<\/strong><\/h3>\n\n\n\n

DOI<\/strong>: 10.48087\/BJMS.2026.130303<\/p>\n\n\n\n

Authors:<\/strong>\u00a0Sofiane GHEMRI, Adlane REZZOUG, Sihem ATOUB, Nachida BENMIRADI<\/p>\n\n\n\n

Affiliations:<\/strong> Universit\u00e9 des Sciences de la Sant\u00e9 El Moudjahid Dr Youcef El Khatib, Facult\u00e9 de M\u00e9decine, Alger ; EHS Dr Maouche Mohand Amokrane, Alger, Alg\u00e9rie.<\/p>\n\n\n\n

Abstract<\/strong><\/p>\n\n\n\n

Background:<\/strong> While Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a recognized cardiovascular risk factor, its impact on the anatomical extent of coronary lesions during acute coronary syndrome (ACS) remains debated. Chronic intermittent hypoxia may promote more diffuse atherosclerosis. Objective:<\/strong> This study aimed to determine whether the presence and severity of OSAHS are associated with increased clinical severity and multivessel coronary artery disease in patients admitted for a first episode of non-ST-segment elevation acute coronary syndrome (NSTE-ACS). Methods:<\/strong> This prospective, single-center study included 241 consecutive patients admitted for an inaugural NSTE-ACS between September 2019 and September 2020. All patients underwent coronary angiography and OSAHS screening via type III respiratory polygraphy during hospitalization. Severe OSAHS was defined as an Apnea-Hypopnea Index (AHI) >30 events\/h. Disease severity was assessed using the GRACE risk score, echocardiography, and the number of stenosed coronary vessels. Results:<\/strong> The overall prevalence of OSAHS (AHI >15) was 52.7%, with a large proportion of severe forms. Multivariate analysis demonstrated that severe OSAHS was associated with more diffuse anatomical disease. Specifically, compared to single-vessel disease, the presence of severe OSAHS significantly increased the risk of two-vessel disease (OR = 2.30; 95% CI: 1.07\u20134.98; p = 0.019) and showed a strong trend toward three-vessel disease (OR = 2.07; 95% CI: 0.93\u20134.63; p = 0.048). Clinically, this anatomical diffusion was accompanied by an increased severity profile, with severe OSAHS being strongly associated with a GRACE risk score >140 (OR = 2.27; 95% CI: 1.30\u20133.98; p = 0.002) and the presence of left ventricular wall motion abnormalities (OR = 2.72; p = 0.013). Conclusion:<\/strong> Among patients admitted for an inaugural NSTE-ACS, severe OSAHS goes beyond being a mere comorbidity to establish itself as an independent predictor of coronary artery disease extent. It is associated with more diffuse angiographic lesions (multivessel disease) and a higher clinical risk profile upon admission, which may directly impact the revascularization strategy.<\/p>\n\n\n\n

Keywords:<\/strong> Severe OSAHS, NSTE-ACS, Coronary Angiography, Multivessel Disease, GRACE Score.<\/p>\n","protected":false},"excerpt":{"rendered":"

Fulltext (PDF) DOI: 10.48087\/BJMS.2026.130303 Authors:\u00a0Sofiane GHEMRI, Adlane REZZOUG, Sihem ATOUB, Nachida BENMIRADI Affiliations: Universit\u00e9 des Sciences de la Sant\u00e9 El Moudjahid Dr Youcef El Khatib, Facult\u00e9 de M\u00e9decine, Alger ; EHS Dr Maouche Mohand Amokrane, Alger, Alg\u00e9rie. Abstract Background: While Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a recognized cardiovascular risk factor, its impact on the anatomical extent … Continuer la lecture de Is severe sleep apnea syndrome associated with more extensive coronary involvement? Angiographic and clinical analysis in 241 patients admitted for a first NSTE-ACS: an Algerian prospective study<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-702","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/702","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/comments?post=702"}],"version-history":[{"count":2,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/702\/revisions"}],"predecessor-version":[{"id":761,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/702\/revisions\/761"}],"wp:attachment":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/media?parent=702"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/categories?post=702"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/tags?post=702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}