{"id":575,"date":"2025-12-28T18:17:21","date_gmt":"2025-12-28T18:17:21","guid":{"rendered":"https:\/\/batnajms.net\/?p=575"},"modified":"2025-12-28T19:18:39","modified_gmt":"2025-12-28T19:18:39","slug":"zidane","status":"publish","type":"post","link":"https:\/\/batnajms.net\/index.php\/2025\/12\/28\/zidane\/","title":{"rendered":"Clinico-epidemiological, therapeutic and prognostic aspects of cavum cancer in Mostaganem"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\" id=\"block-c2f138d4-0208-4b99-af09-93c83eb26d35\"><strong><a href=\"https:\/\/batnajms.net\/wp-content\/uploads\/Archives\/2026\/01\/BJMS_Zidane.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Fulltext\u00a0<\/strong><\/a>(PDF)<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>DOI<\/strong>: 10.48087\/BJMS.2026.130103<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Authors:<\/strong>&nbsp;Habib ZIDANE, Nesrine ZAHI, Mohamed Hadjar KHERFANE.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Keywords:<\/strong>&nbsp;nasopharyngeal cancer, treatment, induction chemotherapy, survival<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Abstract<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Introduction<\/strong>: Nasopharyngeal carcinoma is common in Algeria. Its worldwide incidence is geographically dependent, diagnosis is often delayed, and prognosis remains guarded despite high radiosensitivity. <strong>Methods<\/strong>: This retrospective study was conducted from January 2021 to August 2024 in the medical oncology department of Mostaganem University Hospital and included 49 cases of nasopharyngeal carcinoma. <strong>Results<\/strong>: The mean age was 50.2 years, with 83.7% males (n=41) and 73.5% (n=36) non-smokers. The median time to diagnosis was 4 months (range: 1-20 months). Cervical lymphadenopathy was palpated in all patients, while the oto-rhino-neurological triad was present in 10.2% of cases (n=5). Undifferentiated nasopharyngeal carcinoma was diagnosed in 93.9% of cases (n=46). T4 tumors were found in 24.5% (n=12) and M1 disease in 8.2% (n=4). Chemotherapy was administered to 47 patients, with neoadjuvant chemotherapy in 89.4% (n=42). The PTX protocol (cisplatin, docetaxel, capecitabine) was used in the majority of cases (n=40), with a mean of 3.4 cycles (range: 1-9 cycles). The complete response rate to neoadjuvant chemotherapy was 16.7% (n=7). Radiotherapy was performed in 42 patients, with a mean delivered dose of 62.46 Gy (range: 30-70 Gy). Five patients died during the study period, yielding a three-year overall survival rate of 89.6%. <strong>Conclusion<\/strong>: Nasopharyngeal carcinoma is a relatively common tumor in Algeria, often diagnosed at an advanced stage. It is chemosensitive and radiosensitive, with radiotherapy as the primary treatment. Survival analysis showed a trend toward better outcomes in male patients under 60 years of age with minimal lymph node involvement (N1); however, these associations did not reach statistical significance. Further studies are needed to establish a comprehensive profile of nasopharyngeal carcinoma in Algeria.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fulltext\u00a0(PDF) DOI: 10.48087\/BJMS.2026.130103 Authors:&nbsp;Habib ZIDANE, Nesrine ZAHI, Mohamed Hadjar KHERFANE. Keywords:&nbsp;nasopharyngeal cancer, treatment, induction chemotherapy, survival Abstract Introduction: Nasopharyngeal carcinoma is common in Algeria. Its worldwide incidence is geographically dependent, diagnosis is often delayed, and prognosis remains guarded despite high radiosensitivity. Methods: This retrospective study was conducted from January 2021 to August 2024 in the &hellip; <a href=\"https:\/\/batnajms.net\/index.php\/2025\/12\/28\/zidane\/\" class=\"more-link\">Continuer la lecture de <span class=\"screen-reader-text\">Clinico-epidemiological, therapeutic and prognostic aspects of cavum cancer in Mostaganem<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-575","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/575","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/comments?post=575"}],"version-history":[{"count":2,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/575\/revisions"}],"predecessor-version":[{"id":602,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/posts\/575\/revisions\/602"}],"wp:attachment":[{"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/media?parent=575"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/categories?post=575"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/batnajms.net\/index.php\/wp-json\/wp\/v2\/tags?post=575"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}